UBXN1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD218676A
Western blot analysis of Mouse brain tissue Hela and HEPG2 cell lysates using UBXN1 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using UBXN1 Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using UBXN1 Polyclonal Antibody at dilution of 1:35(×200)
Product Name
UBXN1 Polyclonal Antibody
Catalog Number
RD218676A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.
Immunogen Information
Immunogen
Full length fusion protein
Swissprot
Q04323
Synonyms
2B284930455J02RikD19Ertd721eMGC124706MGC6696mY33KProtein 2B28RGD1309471SAKS1SAPK substrate protein 1T25529UBA/UBX 33.3 kDa proteinUBX domain containing protein 1UBX domain protein 1UBXD10UBXN1
Calculated MW
33 kDa
Observed MW
Refer to figures
Gene Accession
BC001372
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
1.2 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas