UGT1A4 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD267676A
Immunohistochemistry of paraffin-embedded Human kidney cancer using UGT1A4 Polyclonal Antibody at dilution of  1:200 (40x lens).
Immunohistochemistry of paraffin-embedded Human kidney cancer using UGT1A4 Polyclonal Antibody at dilution of 1:200 (40x lens).
Variation
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Overview
Circle
Product Name
UGT1A4 Polyclonal Antibody
Catalog Number
RD267676A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Circle
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins.
Immunogen Information
Circle
Immunogen
Recombinant fusion protein of human UGT1A4 (NP_009051.1).
Gene ID
54657
Swissprot
P22310
Synonyms
UGT1A4HUG-BR2UDPGTUDPGT 1-4UGT-1DUGT1-04UGT1.4UGT1A4SUGT1DUDPGT1-4
Applications
Circle
Reactivity
Human,Mouse
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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