Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
Immunogen Information
Immunogen
Synthetic peptide of human UPP2
Swissprot
O95045
Synonyms
Liver specific uridine phosphorylaseUDRPASE2UP2UPase 2UPASE2UPP 2UPP2UPP2UrdPase 2Uridine phosphorylase 2
Calculated MW
36 kDa
Gene Accession
NP_775491
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-150, ELISA 1:1000-2000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4