This gene encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. This gene may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 22.
Immunogen Information
Immunogen
Synthetic peptide of human URI1
Swissprot
O94763
Synonyms
C19orf2Chromosome 19 open reading frame 2NNX3NNX3 proteinPPP1R19Protein NNX3Protein phosphatase 1 regulatory subunit 19RMPRMPRNA polymerase II subunit 5 mediating proteinRNA polymerase II subunit 5-mediating proteinRPB5 mediating proteinRPB5