VAV3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD82111A
Immunofluorescence analysis of HeLa cells using VAV3 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of L929 cells using VAV3 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Product Name
VAV3 Polyclonal Antibody
Catalog Number
RD82111A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Immunogen Information
Immunogen
Recombinant fusion protein of human VAV3 (NP_006104.4).
Gene ID
10451
Swissprot
Q9UKW4
Synonyms
VAV3
Applications
Reactivity
Human,Mouse
Tested Applications
IF
Conjugation
Unconjugated
Dilution
IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas