Vcam1 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Western blot with Lbp Polyclonal antibody at dilution of 1:500.lane 1:Mouse spleen,lane 2:Rat kidney,lane 3:Rat spleen
Western blot with Lbp Polyclonal antibody at dilution of 1:500.lane 1:Mouse spleen,lane 2:Rat kidney,lane 3:Rat spleen
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Overview

Circle
Product Name
Vcam1 Polyclonal Antibody
Catalog Number
RD90648A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation. Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins. During inflammatory responses,binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration. Serves also as a quality-control checkpoint for entry into bone marrow by providing a 'don't-eat-me' stamping in the context of major histocompatibility complex(MHC) class-I presentation.

Immunogen Information

Circle
Immunogen
Recombinant Rat Vcam1 protein expressed by Mammalian
Swissprot
P29534
Synonyms
Vcam1Vcam-1CD106V-CAM 1VCAM-1Vascular cell adhesion protein 1

Applications

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Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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