Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene.
Immunogen Information
Immunogen
Fusion protein of human VPS45
Swissprot
Q9NRW7
Synonyms
h-VPS45H1H1VPS45HGNC:14579hlVps45Leucocyte vacuolar protein sorting 45OTTHUMP00000014482Vacuolar protein sorting 45 homolog (S. cerevisiae)Vacuolar protein sorting 45A (yeast homolog)Vacuolar protein sorting 45AVacuolar protein sorting 45B (yeas
Gene Accession
BC012932
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-150, ELISA 1:2000-10000
Concentration
1.1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4