The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described.
Immunogen Information
Immunogen
Recombinant fusion protein of human VSX1 (NP_055403.2).
Gene ID
30813
Swissprot
Q9NZR4
Synonyms
VSX1CAASDSKTCNKTCN1PPCDPPCD1PPDRINX
Calculated MW
14 kDa/22 kDa/24 kDa/29 kDa/32 kDa/38 kDa/39 kDa
Observed MW
40 kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
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