This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant protein of human WDR83
Swissprot
Q9BRX9
Synonyms
MAPK organizer 1MGC4238Mitogen activated protein kinase organizer 1>Mitogen-activated protein kinase organizer 1MORG 1WD repeat domain-containing protein 83wdr83WDR83
Gene Accession
BC005870
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4