This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains four WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Alternatively spliced transcript variants have been observed but their full-length nature has not been determined.
Immunogen Information
Immunogen
Synthetic peptide of human WFDC3
Swissprot
Q8IUB2
Synonyms
dJ447F3.3OTTHUMP00000031166OTTHUMP00000196627protease inhibitor WAP14Putative protease inhibitor WAP14WAP four-disulfide core domain protein 3WAP14WFDC3WFDC3whey acidic protein 14