This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated witHuman, Mouseultiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12.
Immunogen Information
Immunogen
Synthetic peptide of human WWOX
Swissprot
Q9NZC7
Synonyms
5330426P09Rik9030416C10RikAberrant WW domain-containing oxidoreductaseD16S432EEC 1.1.1.-EIEE28FORFRA16DFragile site FRA16D oxidoreductaseFragile site FRA16D OxireductaseHHCMA56MGC55975PRO0128Putative oxidoreductaseSCAR12SDR41C1Short chain
Calculated MW
47 kDa
Gene Accession
NP_057457
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-2000, IHC 1:20-100, ELISA 1:2000-5000
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4