The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
Immunogen Information
Immunogen
Synthetic peptide of human XPO1
Swissprot
O14980
Synonyms
Chromosome region maintenance 1 protein homologCRM 1CRM1 homologDKFZp686B1823embExp 1Exp1Exportin 1Exportin-1Exportin1XPO 1xpo1XPO1