This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen Information
Immunogen
Synthesized peptide derived from the Internal region of human YAP
Swissprot
P46937
Synonyms
65 kDa Yes associated protein65 kDa Yes-associated proteinCOB1YAp 1YAP 65YAPYAP1YAP1YAP2YAP65yes -associated protein deltaYes associated protein 1 65kDaYes associated protein 1Yes associated protein 2yes associated protein betaYKIYorkie ho
Calculated MW
49 kDa
Observed MW
67 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-p,IF,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4