YWHAE Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD80451A
Immunofluorescence analysis of H9C2 cells using YWHAE Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of L929 cells using YWHAE Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U2OS cells using YWHAE Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Product Name
YWHAE Polyclonal Antibody
Catalog Number
RD80451A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.
Immunogen Information
Immunogen
Recombinant fusion protein of human YWHAE (NP_006752.1).
Gene ID
7531
Swissprot
P62258
Synonyms
YWHAE14-3-3EHEL2KCIP-1MDCRMDS
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IF
Conjugation
Unconjugated
Dilution
IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas