This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells.
Immunogen Information
Immunogen
Synthetic peptide of human ZAK
Swissprot
Q9NYL2
Synonyms
AZKCervical cancer suppressor gene 4 proteinHCCS 4HCCS-4HCCS4Human cervical cancer suppressor gene 4 proteinLeucine zipper and sterile alpha motif containing kinaseLeucine zipper- and sterile alpha motif-containing kinaseMitogen activated protein