ZAP70 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD253219A
Western blot analysis of Jurkat cells using ZAP70 Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ZAP70 Polyclonal Antibody at dilution of 1:50(×200)
Product Name
ZAP70 Polyclonal Antibody
Catalog Number
RD253219A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Zeta-associated protein (ZAP)-70,a member of the Syk family of tyrosine kinases,plays an important role in T-cell receptor signaling,natural killer (NK) cell activation and early B-cell development. ZAP-70 is expressed in a subset of cases of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) with unmutated immunoglobulin heavy-chain variable region (IgVH) genes and is associated with poor clinical outcome.
Immunogen Information
Immunogen
Synthetic peptide of human ZAP70
Swissprot
P43403
Synonyms
70 kDa zeta associated protein70 kDa zeta-associated proteinEC 2.7.10.2FLJ17670FLJ17679Selective T cell defectSRKSTDSyk related tyrosine kinaseSyk-related tyrosine kinaseTruncated ZAP kinaseTyrosine protein kinase ZAP70Tyrosine-protein kinase
Calculated MW
70 kDa
Observed MW
Refer to figures
Gene Accession
NP001070
Applications
Reactivity
Human, Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:2000-1:5000
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas