LRF, formerly identified as Pokemon, is a poxvirus zinc finger (POZ) domain-containing transcription factor that influences cell differentiation. LRF (for leukemia/lymphoma related factor) is also known as zinc finger and BTB domain containing 7A, ZBTB7, TIP21, FBI1 and FBI-1. POZ-domain transcription factors contain a POZ or BTB type protein-protein interaction domain at their N-terminus and Kruppel-type zinc fingers at their C-terminus. LRF is inducible during both murine and human preadipocyte differentiation and may contrib-ute to adipogenesis through influencing the switch from cellular proliferation to terminal differentiation.
Immunogen Information
Immunogen
Synthetic peptide of human ZBTB7A
Swissprot
O95365
Synonyms
DKFZp547O146Factor binding IST protein 1Factor that binds to inducer of short transcripts protein 1FBI-1FBI1HIV-1 1st-binding protein 1HIV-1 inducer of short transcripts binding proteinHIV-1 inducer of short transcripts-binding factor 1Leukemia/ly
Calculated MW
61 kDa
Observed MW
Refer to figures
Gene Accession
NP056982
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, ELISA 1:2000-1:5000
Concentration
1.8 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
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