ZCCHC8 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD89996A
Western blot analysis of extracts of various cell lines using ZCCHC8 Polyclonal Antibody at 1:3000 dilution.
Western blot analysis of extracts of various cell lines using ZCCHC8 Polyclonal Antibody at 1:3000 dilution.
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Overview

Circle
Product Name
ZCCHC8 Polyclonal Antibody
Catalog Number
RD89996A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
This gene encodes a scaffold protein which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal proline-rich domain.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human ZCCHC8
Gene ID
55596
Swissprot
Q6NZY4
Synonyms
ZCCHC8
Calculated MW
32kDa/37kDa
Observed MW
30kDa

Applications

Circle
Reactivity
Human,Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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