ZFP42 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western Blot analysis of A549, K562 and PC3 cell using ZFP42 Polyclonal Antibody at dilution of 1:500
Product Name
ZFP42 Polyclonal Antibody
Catalog Number
RD76662A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Rex-1 (for reduced expression), also designated zinc finger protein 42 (ZFP42), is an acidic zinc finger protein. Rex-1 contains four repeats of the zinc finger nucleic acid-binding motif and a potential acidic activator domain, suggesting that it is a regulatory protein. Rex-1 localizes to the nucleus and is highly expressed in embryonic stem (ES) and undifferentiated murine F9 teratocarcinoma cells. At the transcriptional level, expression of Rex-1 is reduced when F9 cells are induced to differentiate by the addition of retinoic acid (RA), and Rex-1 repression is enhanced by E1A. The Oct-3/4 transcription factor can either activate or repress the Rex-1 promoter, depending on the cellular environment, while Oct-6 can lower the expression of Rex-1.
Immunogen Information
Immunogen
Synthetic peptide of human ZFP42
Swissprot
Q96MM3
Synonyms
hREX-1Reduced Expression 1 ProteinReduced expression protein 1Rex-1REX1REX1 transcription factorZfp-42Zfp42ZFP42 zinc finger proteinZFP42Zinc finger protein 42 homologZinc finger protein 754ZNF754
Calculated MW
35 kDa
Gene Accession
NP_777560
Applications
Research Areas