ZFYVE19 (zinc finger, FYVE domain containing 19), also known as MPFYVE (MLL partner containing FYVE domain), is a 471 amino acid protein that contains one FYVE-type zinc finger. Expressed in heart, brain, kidney, skeletal muscle and liver, ZFYVE19 may participate in transcriptional regulation events within the cell. Defects in the gene encoding ZFYVE19 are associated with acute myeloblastic leukemia (AML), a rapidly progressing cancer of the myeloid line of white blood cells that is characterized by fever, anemia, bone pain, shortness of breath and frequent infections. Three isoforms of ZFYVE19 exist due to alternative splicing events.
Immunogen Information
Immunogen
Synthetic peptide of human ZFYVE19
Swissprot
Q96K21
Synonyms
Abscission/NoCut checkpoint regulatorANCHRMLL partner containing FYVE domainMPFYVEZFY19ZFYVE 19Zfyve19Zinc finger FYVE domain containing protein 19Zinc finger FYVE domain-containing protein 19Zinc finger FYVE type containing 19Zinc fingerFYVE d