ZKSCAN3 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD218451A
Immunohistochemistry of paraffin-embedded Human lung cancer tissue  using ZKSCAN3 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using ZKSCAN3 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue  using ZKSCAN3 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ZKSCAN3 Polyclonal Antibody at dilution of 1:50(×200)
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Overview

Circle
Product Name
ZKSCAN3 Polyclonal Antibody
Catalog Number
RD218451A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.

Immunogen Information

Circle
Immunogen
Fusion protein of human ZKSCAN3
Swissprot
Q9BRR0
Synonyms
dJ874C20.1mszf35SCAN-KRAB-zinc finger proteinSkz1Zf47Zfp-47ZFP306Zfp307Zfp47Zinc finger and SCAN domain containing protein 13Zinc finger and SCAN domain-containing protein 13Zinc finger protein 306Zinc finger protein 306isoform CRA_aZinc fi
Gene Accession
BC006118

Applications

Circle
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:40-1:250, ELISA 1:5000-1:10000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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