ZNF281 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD87493A
Western blot analysis of extracts of mouse spleen using ZNF281 Polyclonal Antibody at 1:3000 dilution.
Western blot analysis of extracts of mouse spleen using ZNF281 Polyclonal Antibody at 1:3000 dilution.
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Overview

Circle
Product Name
ZNF281 Polyclonal Antibody
Catalog Number
RD87493A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity. Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human ZNF281
Gene ID
23528
Swissprot
Q9Y2X9
Synonyms
ZNF281ZBP-99ZNP-99
Calculated MW
38kDa
Observed MW
38kDa

Applications

Circle
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:1000-1:3000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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