ZNF281 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD252368A
Western blot analysis of A549 cell using ZNF281 Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using ZNF281 Polyclonal Antibody at dilution of 1:70(×200)
Immunohistochemistry of paraffin-embedded Human brain tissue using ZNF281 Polyclonal Antibody at dilution of 1:70(×200)
Product Name
ZNF281 Polyclonal Antibody
Catalog Number
RD252368A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99 or ZNP-99 (zinc finger DNA-binding protein 99), is a zinc finger protein that belongs to the Krüppel C2H2-type zinc finger protein family. It is expressed ubiquitously at low levels with predominant expression in kidney, liver, lymphocytes and placenta. ZNF281 localizes to the nucleus and contains four C2H2-type zinc fingers. ZNF281 plays a role in repressing the transcription of a variety of genes including Gastrin and ODC (ornithine decarboxylase). In particular, ZNF281 functions by binding to the G-rich box in the enhancer region of the gene. Upon DNA damage, ZNF281 may become phosphorylated by Atm or ATR.
Immunogen Information
Immunogen
Fusion protein of human ZNF281
Swissprot
Q9Y2X9
Synonyms
GC box binding zinc finger protein 1GC-box-binding zinc finger protein 1GZP1Transcription factor ZBP-99ZBP 99ZBP99zfp281Zinc finger DNA binding protein 99Zinc finger DNA-binding protein 99Zinc finger protein 281ZN281ZNF281ZNP 99ZNP 99 transcr
Calculated MW
97 kDa
Observed MW
Refer to figures
Gene Accession
BC060820
Applications
Reactivity
Human, Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:60-1:450, ELISA 1:5000-1:10000
Concentration
1.2 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.