Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF85 (Zinc finger protein 85), also known as zinc finger protein HPF4 or HTF1, is a member of the ZNF91 family and is thought to be involved in transcriptional regulation. ZNF85 is highly expressed in testicular tissue and localizes to the nucleus. ZNF85 contains sixteen C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNA-binding and transcriptional regulation.
Immunogen Information
Immunogen
Synthetic peptide of human ZNF85
Swissprot
Q03923
Synonyms
HPF 4HPF4HTF 1HTF1MGC78566Zinc finger protein 85Zinc finger protein HPF4Zinc finger protein HTF1ZNF 85ZNF85ZNF85